ea0081p185 | Reproductive and Developmental Endocrinology | ECE2022
Bouca Bruno
, Cascao Mariana
, Fiuza Pedro
, Amaral Sara
, Bogalho Paula
, Silva-Nunes Jose
Introduction: 17 alpha-hydroxylase deficiency (17OHD) is a rare autosomal recessive disease caused by mutations in the CYP17A gene, representing 1% of cases of Congenital Adrenal Hyperplasia (CAH). The accumulation of mineralocorticoids and the glucocorticoid effect of corticosterone induce high blood pressure (HBP) and hypokalemia.Clinical Case: A 44 year-old female reporting HBP since the age of 20 years and without chronic medication, presented at the...